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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Weight control: Which Medications Are Safest? (143 Drugs Compared)

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143 medications are used for Weight control, with 28,660 combined adverse event reports. The most reported drugs for Weight control are TIRZEPATIDE and SEMAGLUTIDE.

28,660
Total Reports
143
Drugs Used

All Medications for Weight control Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
TIRZEPATIDE Zepbound 17,354 455 5,527 0.5%
SEMAGLUTIDE WEGOVY 6,378 792 11,258 1.3%
BUPROPION\NALTREXONE - 2,842 30 628 0.4%
LIRAGLUTIDE Victoza 1,046 994 4,819 4.3%
LORCASERIN - 243 15 187 0.6%
ORLISTAT Xenical 235 31 329 0.5%
DULAGLUTIDE Trulicity 180 1,054 6,536 1.4%
PHENTERMINE Phentermine Hydrochloride 79 222 399 12.5%
TOPIRAMATE Topiramate 65 3,527 7,098 12.3%
BELVIQ - 58 1 7 0.3%
METFORMIN Metformin Hydrochloride 54 11,550 40,702 12.7%
BUPROPION Bupropion Hydrochloride (XL) 23 8,577 10,246 24.1%
UNSPECIFIED INGREDIENT - 22 6,132 11,236 23.4%
FUROSEMIDE Furosemide 21 6,131 30,446 11.8%
PHENTERMINE\TOPIRAMATE - 21 9 170 0.2%
EXENATIDE Exenatide 18 1,228 2,512 3.9%
ALLI - 16 0 14 N/A
DIETARY SUPPLEMENT - 16 451 842 23.0%
NALTREXONE NALTREXONE HYDROCHLORIDE 16 1,106 2,843 4.3%
CHORIOGONADOTROPIN ALFA Ovidrel 12 43 1,199 1.6%

View all 143 drugs →

Most Reported Drugs for Weight control

#1 most reported
#2 most reported
#3 most reported