Does ACETAMINOPHEN Cause Nephrolithiasis? 391 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 391 reports of Nephrolithiasis have been filed in association with ACETAMINOPHEN (Hydrocodone Bitartrate and Acetaminophen). This represents 0.3% of all adverse event reports for ACETAMINOPHEN.
391
Reports of Nephrolithiasis with ACETAMINOPHEN
0.3%
of all ACETAMINOPHEN reports
1
Deaths
83
Hospitalizations
How Dangerous Is Nephrolithiasis From ACETAMINOPHEN?
Of the 391 reports, 1 (0.3%) resulted in death, 83 (21.2%) required hospitalization, and 2 (0.5%) were considered life-threatening.
Is Nephrolithiasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ACETAMINOPHEN. However, 391 reports have been filed with the FAERS database.
What Other Side Effects Does ACETAMINOPHEN Cause?
Drug ineffective (17,522)
Toxicity to various agents (16,128)
Off label use (9,410)
Vomiting (9,055)
Pain (8,573)
Fatigue (8,202)
Overdose (7,917)
Nausea (7,245)
Rash (7,107)
Headache (7,084)
What Other Drugs Cause Nephrolithiasis?
ADALIMUMAB (2,416)
ETANERCEPT (1,292)
INFLIXIMAB (981)
METHOTREXATE (979)
ABATACEPT (788)
TOPIRAMATE (768)
CERTOLIZUMAB PEGOL (735)
RITUXIMAB (709)
TOFACITINIB (699)
SODIUM OXYBATE (698)
Which ACETAMINOPHEN Alternatives Have Lower Nephrolithiasis Risk?
ACETAMINOPHEN vs ACETAMINOPHEN AND OR DEXTROMETHORPHAN AND OR DIPHENHYDRAMINE AND OR GUAIFENESIN AND OR PHENYLEPHRINE AND OR PSEUDOEPHEDRINE
ACETAMINOPHEN vs ACETAMINOPHEN W/HYDROCODONE
ACETAMINOPHEN vs ACETAMINOPHEN\ASPIRIN\CAFFEINE
ACETAMINOPHEN vs ACETAMINOPHEN\ASPIRIN\CAFFEINE\SALICYLAMIDE
ACETAMINOPHEN vs ACETAMINOPHEN\BELLADONNA LEAF\CAFFEINE\OPIUM