AFATINIB for Product used for unknown indication: Side Effects & Safety Data
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There are 916 adverse event reports in the FDA FAERS database where AFATINIB was used for Product used for unknown indication.
Most Reported Side Effects for AFATINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 2,001 | 32.9% | 351 | 984 |
| Malignant neoplasm progression | 1,622 | 26.7% | 445 | 283 |
| Rash | 808 | 13.3% | 131 | 315 |
| Stomatitis | 468 | 7.7% | 77 | 234 |
| Death | 443 | 7.3% | 443 | 63 |
| Nausea | 430 | 7.1% | 69 | 280 |
| Decreased appetite | 412 | 6.8% | 85 | 255 |
| Vomiting | 381 | 6.3% | 67 | 271 |
| Paronychia | 344 | 5.7% | 62 | 133 |
| Dehydration | 323 | 5.3% | 56 | 276 |
| Fatigue | 256 | 4.2% | 52 | 128 |
| Metastases to central nervous system | 248 | 4.1% | 72 | 58 |
| Asthenia | 221 | 3.6% | 46 | 151 |
| Off label use | 204 | 3.4% | 64 | 37 |
| Drug ineffective | 203 | 3.3% | 31 | 47 |
Other Indications for AFATINIB
Non-small cell lung cancer (2,010)
Lung adenocarcinoma (876)
Lung neoplasm malignant (824)
Egfr gene mutation (780)
Non-small cell lung cancer metastatic (285)
Lung adenocarcinoma stage iv (146)
Adenocarcinoma (144)
Squamous cell carcinoma of head and neck (76)
Non-small cell lung cancer stage iv (74)
Lung cancer metastatic (68)
Other Drugs Used for Product used for unknown indication
OXYCODONE (129,391)
ADAPALENE (91,681)
APIXABAN (88,417)
ETANERCEPT (71,866)
SACUBITRIL\VALSARTAN (69,693)
ACETAMINOPHEN (68,427)
AVOBENZONE\OCTISALATE\OCTOCRYLENE (65,206)
ADALIMUMAB (63,549)
EVOLOCUMAB (60,696)
MORPHINE (59,440)