Does AFATINIB Cause Metastases to central nervous system? 248 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 248 reports of Metastases to central nervous system have been filed in association with AFATINIB (Gilotrif). This represents 4.1% of all adverse event reports for AFATINIB.
248
Reports of Metastases to central nervous system with AFATINIB
4.1%
of all AFATINIB reports
72
Deaths
58
Hospitalizations
How Dangerous Is Metastases to central nervous system From AFATINIB?
Of the 248 reports, 72 (29.0%) resulted in death, 58 (23.4%) required hospitalization, and 8 (3.2%) were considered life-threatening.
Is Metastases to central nervous system Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AFATINIB. However, 248 reports have been filed with the FAERS database.
What Other Side Effects Does AFATINIB Cause?
Diarrhoea (2,001)
Malignant neoplasm progression (1,622)
Rash (808)
Stomatitis (468)
Death (443)
Nausea (430)
Decreased appetite (412)
Vomiting (381)
Paronychia (344)
Dehydration (323)
What Other Drugs Cause Metastases to central nervous system?
TRASTUZUMAB (1,180)
CAPECITABINE (663)
OSIMERTINIB (560)
PERTUZUMAB (540)
PACLITAXEL (498)
NIVOLUMAB (495)
DABRAFENIB (451)
CARBOPLATIN (413)
DOCETAXEL (410)
ADO-TRASTUZUMAB EMTANSINE (386)
Which AFATINIB Alternatives Have Lower Metastases to central nervous system Risk?
AFATINIB vs AFINITOR
AFATINIB vs AFLIBERCEPT
AFATINIB vs AGALSIDASE ALFA
AFATINIB vs AGALSIDASE BETA
AFATINIB vs AGOMELATINE