Does AFATINIB Cause Cardiac failure? 39 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 39 reports of Cardiac failure have been filed in association with AFATINIB (Gilotrif). This represents 0.6% of all adverse event reports for AFATINIB.
39
Reports of Cardiac failure with AFATINIB
0.6%
of all AFATINIB reports
9
Deaths
16
Hospitalizations
How Dangerous Is Cardiac failure From AFATINIB?
Of the 39 reports, 9 (23.1%) resulted in death, 16 (41.0%) required hospitalization, and 4 (10.3%) were considered life-threatening.
Is Cardiac failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AFATINIB. However, 39 reports have been filed with the FAERS database.
What Other Side Effects Does AFATINIB Cause?
Diarrhoea (2,001)
Malignant neoplasm progression (1,622)
Rash (808)
Stomatitis (468)
Death (443)
Nausea (430)
Decreased appetite (412)
Vomiting (381)
Paronychia (344)
Dehydration (323)
What Other Drugs Cause Cardiac failure?
SACUBITRIL\VALSARTAN (4,504)
FUROSEMIDE (1,841)
APIXABAN (1,575)
CYCLOPHOSPHAMIDE (1,514)
DOXORUBICIN (1,367)
ADALIMUMAB (1,278)
DEXAMETHASONE (1,271)
TREPROSTINIL (1,168)
BISOPROLOL (1,159)
LENALIDOMIDE (1,115)
Which AFATINIB Alternatives Have Lower Cardiac failure Risk?
AFATINIB vs AFINITOR
AFATINIB vs AFLIBERCEPT
AFATINIB vs AGALSIDASE ALFA
AFATINIB vs AGALSIDASE BETA
AFATINIB vs AGOMELATINE