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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Cardiac failure: Which Medications Cause It? (56,322 Reports Across 1,337 Drugs)

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Cardiac failure has been reported as an adverse event with 1,337 different drugs in the FDA's FAERS database, with 56,322 total reports. 17,506 of these reports resulted in death.The drugs most commonly associated with Cardiac failure are SACUBITRIL\VALSARTAN, FUROSEMIDE, and APIXABAN.

56,322
Total Reports
1,337
Drugs Involved
17,506
Deaths
31,898
Hospitalizations
66.2 yrs
Average Patient Age
49.6% / 50.4%
Female / Male

Which Drugs Cause Cardiac failure Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
SACUBITRIL\VALSARTAN 4,504 4.1% 1,164 2,175 204
FUROSEMIDE 1,841 3.6% 346 1,385 186
APIXABAN 1,575 1.0% 449 862 121
CYCLOPHOSPHAMIDE 1,514 1.2% 507 801 235
DOXORUBICIN 1,367 1.7% 412 645 202
ADALIMUMAB 1,278 0.3% 223 643 48
DEXAMETHASONE 1,271 1.0% 441 762 176
TREPROSTINIL 1,168 1.3% 402 940 81
BISOPROLOL 1,159 4.2% 209 870 100
LENALIDOMIDE 1,115 0.3% 398 634 95
RITUXIMAB 1,093 0.6% 363 569 119
MACITENTAN 1,070 2.4% 446 793 72
AMBRISENTAN 992 1.2% 262 707 31
ASPIRIN 947 1.0% 203 693 78
METHOTREXATE 916 0.4% 241 545 112
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM 911 1.0% 727 500 3
PREDNISONE 881 0.6% 266 583 119
ATORVASTATIN 874 1.1% 127 681 64
TRASTUZUMAB 856 1.8% 105 375 116
RAMIPRIL 842 2.6% 86 671 53

View all 1,337 drugs →

Top 3 Drugs Associated With Cardiac failure

4,504 reports
1,841 reports
1,575 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)