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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Death: Which Medications Cause It? (660,423 Reports Across 2,441 Drugs)

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Death has been reported as an adverse event with 2,441 different drugs in the FDA's FAERS database, with 660,423 total reports. 657,320 of these reports resulted in death.The drugs most commonly associated with Death are OXYCODONE, LENALIDOMIDE, and APIXABAN.

660,423
Total Reports
2,441
Drugs Involved
657,320
Deaths
62,083
Hospitalizations
67.2 yrs
Average Patient Age
46.1% / 53.9%
Female / Male

Which Drugs Cause Death Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
OXYCODONE 23,259 12.2% 23,233 808 53
LENALIDOMIDE 19,213 5.5% 19,190 1,415 138
APIXABAN 18,501 11.6% 18,461 627 116
MORPHINE 17,960 14.9% 17,932 686 67
ACETAMINOPHEN\OXYCODONE 17,849 17.9% 17,832 482 10
FENTANYL 16,577 17.5% 16,552 666 36
DENOSUMAB 16,545 11.1% 16,459 663 68
ACETAMINOPHEN\HYDROCODONE 16,341 15.0% 16,332 528 10
HYDROMORPHONE 15,276 18.3% 15,263 594 106
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM 13,789 14.7% 13,788 1,337 6
BUPRENORPHINE 13,604 16.6% 13,594 378 7
OXYMORPHONE 13,351 35.1% 13,341 296 0
HYDROCODONE 13,014 27.2% 13,006 380 5
ASPIRIN\OXYCODONE 12,322 47.8% 12,314 280 0
DARBEPOETIN ALFA 12,264 37.4% 12,260 2,158 593
TAPENTADOL 11,560 39.6% 11,552 311 1
NIVOLUMAB 11,216 12.8% 11,211 780 116
OSIMERTINIB 10,423 37.6% 10,418 239 31
ADALIMUMAB 10,272 2.1% 10,158 744 70
IMATINIB 9,708 22.5% 9,693 350 40

View all 2,441 drugs →

Top 3 Drugs Associated With Death

23,259 reports
19,213 reports
18,501 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922) Malaise (334,268)