Malaise: Which Medications Cause It? (334,268 Reports Across 2,638 Drugs)
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Malaise has been reported as an adverse event with 2,638 different drugs in the FDA's FAERS database, with 334,268 total reports. 16,348 of these reports resulted in death.The drugs most commonly associated with Malaise are ADALIMUMAB, ETANERCEPT, and METHOTREXATE.
334,268
Total Reports
2,638
Drugs Involved
16,348
Deaths
94,240
Hospitalizations
57.7 yrs
Average Patient Age
69.6% / 30.4%
Female / Male
Which Drugs Cause Malaise Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ADALIMUMAB | 15,965 | 3.2% | 1,909 | 6,358 | 1,688 |
| ETANERCEPT | 13,600 | 3.8% | 1,403 | 2,881 | 1,235 |
| METHOTREXATE | 9,970 | 3.9% | 1,666 | 3,831 | 1,916 |
| TOFACITINIB | 9,040 | 5.8% | 1,306 | 2,561 | 1,306 |
| SECUKINUMAB | 8,570 | 5.7% | 1,593 | 3,029 | 1,915 |
| INFLIXIMAB | 7,477 | 5.3% | 1,451 | 3,099 | 1,527 |
| RITUXIMAB | 6,587 | 3.7% | 1,787 | 3,340 | 1,853 |
| PREGABALIN | 6,320 | 6.2% | 890 | 2,057 | 775 |
| PREDNISONE | 6,319 | 4.0% | 1,484 | 3,424 | 1,722 |
| ABATACEPT | 6,251 | 5.4% | 1,313 | 2,476 | 1,488 |
| TOCILIZUMAB | 5,415 | 5.5% | 1,675 | 2,596 | 1,483 |
| OMALIZUMAB | 4,820 | 7.6% | 113 | 2,032 | 287 |
| LEFLUNOMIDE | 4,655 | 8.2% | 1,552 | 2,279 | 1,617 |
| TREPROSTINIL | 4,410 | 4.8% | 282 | 1,626 | 56 |
| CERTOLIZUMAB PEGOL | 4,376 | 4.4% | 1,325 | 2,000 | 1,375 |
| SACUBITRIL\VALSARTAN | 4,299 | 3.9% | 155 | 859 | 117 |
| ACETAMINOPHEN | 4,251 | 3.1% | 1,601 | 2,482 | 1,631 |
| LENALIDOMIDE | 4,201 | 1.2% | 152 | 1,373 | 58 |
| HYDROXYCHLOROQUINE | 4,059 | 6.1% | 1,353 | 1,937 | 1,427 |
| APREMILAST | 4,020 | 2.9% | 1,233 | 1,467 | 1,276 |