Headache: Which Medications Cause It? (460,069 Reports Across 2,934 Drugs)
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Headache has been reported as an adverse event with 2,934 different drugs in the FDA's FAERS database, with 460,069 total reports. 10,216 of these reports resulted in death.The drugs most commonly associated with Headache are ADALIMUMAB, APREMILAST, and ETANERCEPT.
460,069
Total Reports
2,934
Drugs Involved
10,216
Deaths
82,637
Hospitalizations
52.1 yrs
Average Patient Age
73.4% / 26.6%
Female / Male
Which Drugs Cause Headache Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ADALIMUMAB | 19,891 | 4.0% | 1,906 | 5,361 | 1,766 |
| APREMILAST | 17,024 | 12.5% | 1,240 | 1,645 | 1,220 |
| ETANERCEPT | 14,253 | 4.0% | 1,526 | 2,806 | 1,324 |
| TREPROSTINIL | 14,051 | 15.3% | 369 | 3,789 | 126 |
| METHOTREXATE | 11,718 | 4.6% | 1,694 | 4,391 | 2,003 |
| TOFACITINIB | 11,061 | 7.1% | 1,302 | 2,294 | 1,430 |
| RITUXIMAB | 8,747 | 4.9% | 1,880 | 3,873 | 2,019 |
| TOCILIZUMAB | 8,448 | 8.6% | 1,867 | 3,019 | 1,647 |
| INFLIXIMAB | 8,387 | 6.0% | 1,562 | 3,056 | 1,627 |
| ABATACEPT | 8,184 | 7.0% | 1,422 | 2,532 | 1,635 |
| HUMAN IMMUNOGLOBULIN G | 7,885 | 11.2% | 267 | 1,621 | 78 |
| AMBRISENTAN | 7,325 | 8.5% | 203 | 1,884 | 36 |
| DUPILUMAB | 7,182 | 1.9% | 10 | 429 | 18 |
| ACETAMINOPHEN | 7,084 | 5.2% | 1,784 | 2,836 | 1,738 |
| PREDNISONE | 7,009 | 4.4% | 1,595 | 3,454 | 1,815 |
| LEVOTHYROXINE | 6,425 | 10.4% | 36 | 1,183 | 309 |
| SECUKINUMAB | 6,344 | 4.2% | 1,496 | 2,466 | 1,935 |
| LEFLUNOMIDE | 6,159 | 10.9% | 1,539 | 2,706 | 1,777 |
| CERTOLIZUMAB PEGOL | 6,013 | 6.1% | 1,411 | 2,138 | 1,536 |
| FINGOLIMOD | 5,993 | 8.5% | 30 | 754 | 110 |