Pain: Which Medications Cause It? (471,975 Reports Across 2,684 Drugs)
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Pain has been reported as an adverse event with 2,684 different drugs in the FDA's FAERS database, with 471,975 total reports. 14,357 of these reports resulted in death.The drugs most commonly associated with Pain are OXYCODONE, ADALIMUMAB, and ETANERCEPT.
471,975
Total Reports
2,684
Drugs Involved
14,357
Deaths
89,950
Hospitalizations
54.9 yrs
Average Patient Age
67.5% / 32.5%
Female / Male
Which Drugs Cause Pain Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| OXYCODONE | 55,423 | 29.1% | 2,653 | 3,332 | 1,563 |
| ADALIMUMAB | 37,514 | 7.5% | 2,020 | 9,822 | 2,468 |
| ETANERCEPT | 31,961 | 8.9% | 1,533 | 5,304 | 2,160 |
| METHOTREXATE | 23,773 | 9.4% | 1,981 | 5,911 | 2,764 |
| MORPHINE | 22,787 | 18.9% | 1,078 | 2,691 | 540 |
| TOFACITINIB | 21,659 | 13.9% | 1,649 | 4,320 | 1,979 |
| HYDROMORPHONE | 21,325 | 25.6% | 744 | 1,542 | 207 |
| ABATACEPT | 19,783 | 17.0% | 1,790 | 4,590 | 2,489 |
| TOCILIZUMAB | 18,384 | 18.7% | 1,939 | 4,934 | 2,367 |
| RITUXIMAB | 16,675 | 9.3% | 2,124 | 5,092 | 2,685 |
| LEFLUNOMIDE | 15,594 | 27.6% | 1,725 | 4,155 | 2,420 |
| SECUKINUMAB | 15,244 | 10.1% | 1,659 | 3,575 | 2,285 |
| INFLIXIMAB | 15,061 | 10.7% | 1,800 | 4,291 | 2,460 |
| ACETAMINOPHEN\HYDROCODONE | 14,958 | 13.7% | 497 | 845 | 50 |
| PREDNISONE | 14,347 | 9.1% | 1,740 | 4,561 | 2,249 |
| CERTOLIZUMAB PEGOL | 13,929 | 14.1% | 1,494 | 2,958 | 1,878 |
| HYDROXYCHLOROQUINE | 13,524 | 20.3% | 1,636 | 3,710 | 2,202 |
| PREGABALIN | 12,996 | 12.7% | 695 | 2,603 | 710 |
| ACETAMINOPHEN\OXYCODONE | 11,524 | 11.6% | 1,066 | 1,523 | 613 |
| GOLIMUMAB | 11,443 | 16.5% | 1,581 | 2,876 | 1,934 |