Does METHOTREXATE Cause Pain? 23,773 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 23,773 reports of Pain have been filed in association with METHOTREXATE (Methotrexate). This represents 9.4% of all adverse event reports for METHOTREXATE.
23,773
Reports of Pain with METHOTREXATE
9.4%
of all METHOTREXATE reports
1,981
Deaths
5,911
Hospitalizations
How Dangerous Is Pain From METHOTREXATE?
Of the 23,773 reports, 1,981 (8.3%) resulted in death, 5,911 (24.9%) required hospitalization, and 2,764 (11.6%) were considered life-threatening.
Is Pain Listed in the Official Label?
Yes, Pain is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
Rash (15,519)
What Other Drugs Cause Pain?
OXYCODONE (55,423)
ADALIMUMAB (37,514)
ETANERCEPT (31,961)
MORPHINE (22,787)
TOFACITINIB (21,659)
HYDROMORPHONE (21,325)
ABATACEPT (19,783)
TOCILIZUMAB (18,384)
RITUXIMAB (16,675)
LEFLUNOMIDE (15,594)
Which METHOTREXATE Alternatives Have Lower Pain Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA