Does METHOTREXATE Cause Drug intolerance? 22,555 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 22,555 reports of Drug intolerance have been filed in association with METHOTREXATE (Methotrexate). This represents 8.9% of all adverse event reports for METHOTREXATE.
22,555
Reports of Drug intolerance with METHOTREXATE
8.9%
of all METHOTREXATE reports
1,490
Deaths
4,290
Hospitalizations
How Dangerous Is Drug intolerance From METHOTREXATE?
Of the 22,555 reports, 1,490 (6.6%) resulted in death, 4,290 (19.0%) required hospitalization, and 2,006 (8.9%) were considered life-threatening.
Is Drug intolerance Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 22,555 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
Rash (15,519)
What Other Drugs Cause Drug intolerance?
ADALIMUMAB (15,434)
ETANERCEPT (15,146)
LEFLUNOMIDE (14,142)
HYDROXYCHLOROQUINE (14,093)
ABATACEPT (12,451)
TOCILIZUMAB (11,952)
RITUXIMAB (11,876)
SULFASALAZINE (11,530)
INFLIXIMAB (11,173)
PREDNISONE (8,247)
Which METHOTREXATE Alternatives Have Lower Drug intolerance Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA