Does METHOTREXATE Cause Drug hypersensitivity? 16,677 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 16,677 reports of Drug hypersensitivity have been filed in association with METHOTREXATE (Methotrexate). This represents 6.6% of all adverse event reports for METHOTREXATE.
16,677
Reports of Drug hypersensitivity with METHOTREXATE
6.6%
of all METHOTREXATE reports
1,413
Deaths
3,985
Hospitalizations
How Dangerous Is Drug hypersensitivity From METHOTREXATE?
Of the 16,677 reports, 1,413 (8.5%) resulted in death, 3,985 (23.9%) required hospitalization, and 1,809 (10.8%) were considered life-threatening.
Is Drug hypersensitivity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 16,677 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Rash (15,519)
What Other Drugs Cause Drug hypersensitivity?
ETANERCEPT (12,991)
ADALIMUMAB (11,599)
MORPHINE (11,095)
RITUXIMAB (8,924)
LEFLUNOMIDE (8,148)
INFLIXIMAB (8,119)
TOCILIZUMAB (7,883)
ABATACEPT (7,808)
CODEINE (7,479)
HYDROXYCHLOROQUINE (7,414)
Which METHOTREXATE Alternatives Have Lower Drug hypersensitivity Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA