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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Does METHOTREXATE Cause Fatigue? 19,885 Reports in FDA Database

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According to the FDA Adverse Event Reporting System (FAERS), 19,885 reports of Fatigue have been filed in association with METHOTREXATE (Methotrexate). This represents 7.8% of all adverse event reports for METHOTREXATE.

19,885
Reports of Fatigue with METHOTREXATE
7.8%
of all METHOTREXATE reports
2,005
Deaths
5,458
Hospitalizations

How Dangerous Is Fatigue From METHOTREXATE?

Of the 19,885 reports, 2,005 (10.1%) resulted in death, 5,458 (27.4%) required hospitalization, and 2,615 (13.2%) were considered life-threatening.

Is Fatigue Listed in the Official Label?

Yes, Fatigue is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.

What Other Side Effects Does METHOTREXATE Cause?

Drug ineffective (70,142) Rheumatoid arthritis (29,254) Off label use (24,020) Pain (23,773) Drug intolerance (22,555) Arthralgia (21,831) Nausea (18,715) Joint swelling (17,657) Drug hypersensitivity (16,677) Rash (15,519)

What Other Drugs Cause Fatigue?

ADALIMUMAB (29,420) LENALIDOMIDE (22,956) ETANERCEPT (19,907) RITUXIMAB (15,602) PALBOCICLIB (15,190) PREDNISONE (14,320) TOCILIZUMAB (13,802) TOFACITINIB (13,551) INFLIXIMAB (13,473) ABATACEPT (13,087)

Which METHOTREXATE Alternatives Have Lower Fatigue Risk?

METHOTREXATE vs METHOXSALEN METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA METHOTREXATE vs METHYL ALCOHOL METHOTREXATE vs METHYLCOBALAMIN METHOTREXATE vs METHYLDOPA

Related Pages

METHOTREXATE Full Profile All Fatigue Reports All Drugs Causing Fatigue METHOTREXATE Demographics