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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Fatigue: Which Medications Cause It? (599,248 Reports Across 2,840 Drugs)

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Fatigue has been reported as an adverse event with 2,840 different drugs in the FDA's FAERS database, with 599,248 total reports. 21,386 of these reports resulted in death.The drugs most commonly associated with Fatigue are ADALIMUMAB, LENALIDOMIDE, and ETANERCEPT.

599,248
Total Reports
2,840
Drugs Involved
21,386
Deaths
115,513
Hospitalizations
57.1 yrs
Average Patient Age
65.5% / 34.5%
Female / Male

Which Drugs Cause Fatigue Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
ADALIMUMAB 29,420 5.9% 2,196 7,284 2,266
LENALIDOMIDE 22,956 6.6% 444 2,907 163
ETANERCEPT 19,907 5.6% 1,799 3,838 1,811
METHOTREXATE 19,885 7.8% 2,005 5,458 2,615
RITUXIMAB 15,602 8.7% 2,477 5,183 2,572
PALBOCICLIB 15,190 16.7% 522 1,889 85
PREDNISONE 14,320 9.0% 2,066 5,258 2,532
TOCILIZUMAB 13,802 14.0% 2,217 4,295 2,221
TOFACITINIB 13,551 8.7% 1,643 3,450 1,941
INFLIXIMAB 13,473 9.6% 1,897 3,946 2,172
ABATACEPT 13,087 11.3% 1,763 3,743 2,194
LEFLUNOMIDE 11,959 21.2% 1,825 3,715 2,293
CERTOLIZUMAB PEGOL 11,438 11.5% 1,764 3,013 2,082
HYDROXYCHLOROQUINE 11,342 17.0% 1,721 3,616 2,062
LEVOTHYROXINE 10,494 17.0% 95 1,357 359
SULFASALAZINE 9,684 24.1% 1,644 3,106 2,009
GOLIMUMAB 9,626 13.9% 1,701 2,679 2,013
CETIRIZINE 9,476 19.9% 1,878 2,636 2,215
SECUKINUMAB 9,406 6.2% 1,796 3,142 2,346
FINGOLIMOD 8,901 12.6% 34 921 119

View all 2,840 drugs →

Top 3 Drugs Associated With Fatigue

29,420 reports
22,956 reports
19,907 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922) Malaise (334,268)