Off label use: Which Medications Cause It? (762,782 Reports Across 3,309 Drugs)
Boost Your Natural Energy & Metabolism
Mitolyn — 6 exotic plants to unlock your body's fat-burning power. 90-day guarantee.
Off label use has been reported as an adverse event with 3,309 different drugs in the FDA's FAERS database, with 762,782 total reports. 54,628 of these reports resulted in death.The drugs most commonly associated with Off label use are RITUXIMAB, INFLIXIMAB, and DENOSUMAB.
762,782
Total Reports
3,309
Drugs Involved
54,628
Deaths
141,661
Hospitalizations
52.5 yrs
Average Patient Age
60.2% / 39.8%
Female / Male
Which Drugs Cause Off label use Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| RITUXIMAB | 39,751 | 22.3% | 6,335 | 11,201 | 4,207 |
| INFLIXIMAB | 34,801 | 24.8% | 2,600 | 9,509 | 2,818 |
| DENOSUMAB | 34,612 | 23.2% | 299 | 730 | 55 |
| METHOTREXATE | 24,020 | 9.5% | 3,417 | 7,881 | 3,680 |
| VEDOLIZUMAB | 21,017 | 28.5% | 637 | 5,998 | 256 |
| ETANERCEPT | 20,178 | 5.6% | 1,852 | 4,129 | 2,209 |
| TOCILIZUMAB | 18,256 | 18.5% | 3,347 | 5,844 | 2,763 |
| PREDNISONE | 17,867 | 11.3% | 3,499 | 6,978 | 3,057 |
| LENALIDOMIDE | 17,017 | 4.9% | 1,252 | 3,116 | 250 |
| ADALIMUMAB | 16,417 | 3.3% | 2,187 | 5,051 | 2,662 |
| HYDROXYCHLOROQUINE | 15,318 | 23.0% | 2,584 | 5,688 | 2,773 |
| INFLIXIMAB-DYYB | 14,256 | 55.7% | 274 | 3,718 | 71 |
| MYCOPHENOLATE MOFETIL | 13,474 | 18.0% | 2,365 | 4,340 | 1,474 |
| DEXAMETHASONE | 13,439 | 10.7% | 2,704 | 4,927 | 1,297 |
| CYCLOPHOSPHAMIDE | 12,578 | 9.8% | 2,788 | 3,928 | 1,159 |
| RUXOLITINIB | 12,492 | 18.3% | 1,527 | 1,769 | 111 |
| BEVACIZUMAB | 12,094 | 15.5% | 3,560 | 1,814 | 227 |
| TOFACITINIB | 11,736 | 7.5% | 1,767 | 3,218 | 2,094 |
| ABATACEPT | 10,990 | 9.5% | 1,752 | 3,770 | 2,430 |
| USTEKINUMAB | 10,990 | 12.9% | 1,395 | 2,924 | 1,779 |