Does METHOTREXATE Cause Joint swelling? 17,657 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 17,657 reports of Joint swelling have been filed in association with METHOTREXATE (Methotrexate). This represents 7.0% of all adverse event reports for METHOTREXATE.
17,657
Reports of Joint swelling with METHOTREXATE
7.0%
of all METHOTREXATE reports
1,963
Deaths
4,442
Hospitalizations
How Dangerous Is Joint swelling From METHOTREXATE?
Of the 17,657 reports, 1,963 (11.1%) resulted in death, 4,442 (25.2%) required hospitalization, and 2,559 (14.5%) were considered life-threatening.
Is Joint swelling Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 17,657 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Drug hypersensitivity (16,677)
Rash (15,519)
What Other Drugs Cause Joint swelling?
ETANERCEPT (18,462)
ABATACEPT (18,453)
ADALIMUMAB (18,266)
TOCILIZUMAB (14,831)
LEFLUNOMIDE (13,026)
HYDROXYCHLOROQUINE (11,353)
RITUXIMAB (11,170)
TOFACITINIB (10,686)
INFLIXIMAB (9,853)
SULFASALAZINE (9,673)
Which METHOTREXATE Alternatives Have Lower Joint swelling Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA