Drug hypersensitivity: Which Medications Cause It? (165,477 Reports Across 2,239 Drugs)
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Drug hypersensitivity has been reported as an adverse event with 2,239 different drugs in the FDA's FAERS database, with 165,477 total reports. 3,260 of these reports resulted in death.The drugs most commonly associated with Drug hypersensitivity are METHOTREXATE, ETANERCEPT, and ADALIMUMAB.
165,477
Total Reports
2,239
Drugs Involved
3,260
Deaths
20,238
Hospitalizations
57.7 yrs
Average Patient Age
76.8% / 23.2%
Female / Male
Which Drugs Cause Drug hypersensitivity Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METHOTREXATE | 16,677 | 6.6% | 1,413 | 3,985 | 1,809 |
| ETANERCEPT | 12,991 | 3.6% | 1,194 | 3,225 | 1,415 |
| ADALIMUMAB | 11,599 | 2.3% | 1,495 | 4,127 | 1,685 |
| MORPHINE | 11,095 | 9.2% | 375 | 735 | 267 |
| RITUXIMAB | 8,924 | 5.0% | 1,598 | 3,523 | 1,768 |
| LEFLUNOMIDE | 8,148 | 14.4% | 1,425 | 3,410 | 1,745 |
| INFLIXIMAB | 8,119 | 5.8% | 1,425 | 3,073 | 1,649 |
| TOCILIZUMAB | 7,883 | 8.0% | 1,579 | 3,292 | 1,680 |
| ABATACEPT | 7,808 | 6.7% | 1,354 | 3,178 | 1,652 |
| CODEINE | 7,479 | 34.1% | 286 | 1,006 | 189 |
| HYDROXYCHLOROQUINE | 7,414 | 11.1% | 1,323 | 3,152 | 1,569 |
| SULFASALAZINE | 7,005 | 17.4% | 1,287 | 2,877 | 1,558 |
| GABAPENTIN | 6,833 | 9.2% | 245 | 452 | 127 |
| PREDNISONE | 5,545 | 3.5% | 1,261 | 2,284 | 1,539 |
| CELECOXIB | 5,314 | 16.8% | 958 | 1,607 | 1,142 |
| IBUPROFEN | 5,269 | 6.1% | 215 | 894 | 355 |
| CIPROFLOXACIN | 5,266 | 12.0% | 39 | 369 | 59 |
| TOFACITINIB | 5,106 | 3.3% | 1,206 | 2,028 | 1,435 |
| ACETAMINOPHEN | 4,793 | 3.5% | 1,433 | 1,976 | 1,611 |
| CERTOLIZUMAB PEGOL | 4,237 | 4.3% | 1,230 | 2,088 | 1,423 |