Drug intolerance: Which Medications Cause It? (82,360 Reports Across 1,716 Drugs)
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Drug intolerance has been reported as an adverse event with 1,716 different drugs in the FDA's FAERS database, with 82,360 total reports. 4,039 of these reports resulted in death.The drugs most commonly associated with Drug intolerance are METHOTREXATE, ADALIMUMAB, and ETANERCEPT.
82,360
Total Reports
1,716
Drugs Involved
4,039
Deaths
14,228
Hospitalizations
55.7 yrs
Average Patient Age
72.1% / 27.9%
Female / Male
Which Drugs Cause Drug intolerance Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METHOTREXATE | 22,555 | 8.9% | 1,490 | 4,290 | 2,006 |
| ADALIMUMAB | 15,434 | 3.1% | 1,503 | 3,715 | 1,913 |
| ETANERCEPT | 15,146 | 4.2% | 1,226 | 3,153 | 1,582 |
| LEFLUNOMIDE | 14,142 | 25.0% | 1,514 | 3,354 | 1,921 |
| HYDROXYCHLOROQUINE | 14,093 | 21.1% | 1,340 | 3,422 | 1,781 |
| ABATACEPT | 12,451 | 10.7% | 1,369 | 3,379 | 1,881 |
| TOCILIZUMAB | 11,952 | 12.1% | 1,587 | 3,341 | 1,852 |
| RITUXIMAB | 11,876 | 6.7% | 1,703 | 3,314 | 1,894 |
| SULFASALAZINE | 11,530 | 28.7% | 1,297 | 3,150 | 1,767 |
| INFLIXIMAB | 11,173 | 8.0% | 1,526 | 3,180 | 1,865 |
| PREDNISONE | 8,247 | 5.2% | 1,351 | 2,810 | 1,767 |
| GOLIMUMAB | 7,802 | 11.3% | 1,250 | 2,351 | 1,602 |
| CERTOLIZUMAB PEGOL | 7,740 | 7.8% | 1,254 | 2,256 | 1,622 |
| TOFACITINIB | 7,402 | 4.8% | 1,264 | 2,177 | 1,643 |
| DICLOFENAC | 5,407 | 6.2% | 1,457 | 1,966 | 1,693 |
| ALENDRONATE | 5,384 | 19.3% | 1,325 | 2,230 | 1,673 |
| CETIRIZINE | 5,359 | 11.3% | 1,446 | 1,856 | 1,650 |
| FOLIC ACID | 5,343 | 23.4% | 1,330 | 1,908 | 1,652 |
| DESOXIMETASONE | 5,275 | 45.3% | 1,293 | 1,763 | 1,654 |
| ACETAMINOPHEN | 4,776 | 3.5% | 1,434 | 1,936 | 1,657 |