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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Does METHOTREXATE Cause Headache? 11,718 Reports in FDA Database

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According to the FDA Adverse Event Reporting System (FAERS), 11,718 reports of Headache have been filed in association with METHOTREXATE (Methotrexate). This represents 4.6% of all adverse event reports for METHOTREXATE.

11,718
Reports of Headache with METHOTREXATE
4.6%
of all METHOTREXATE reports
1,694
Deaths
4,391
Hospitalizations

How Dangerous Is Headache From METHOTREXATE?

Of the 11,718 reports, 1,694 (14.5%) resulted in death, 4,391 (37.5%) required hospitalization, and 2,003 (17.1%) were considered life-threatening.

Is Headache Listed in the Official Label?

Yes, Headache is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.

What Other Side Effects Does METHOTREXATE Cause?

Drug ineffective (70,142) Rheumatoid arthritis (29,254) Off label use (24,020) Pain (23,773) Drug intolerance (22,555) Arthralgia (21,831) Fatigue (19,885) Nausea (18,715) Joint swelling (17,657) Drug hypersensitivity (16,677)

What Other Drugs Cause Headache?

ADALIMUMAB (19,891) APREMILAST (17,024) ETANERCEPT (14,253) TREPROSTINIL (14,051) TOFACITINIB (11,061) RITUXIMAB (8,747) TOCILIZUMAB (8,448) INFLIXIMAB (8,387) ABATACEPT (8,184) HUMAN IMMUNOGLOBULIN G (7,885)

Which METHOTREXATE Alternatives Have Lower Headache Risk?

METHOTREXATE vs METHOXSALEN METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA METHOTREXATE vs METHYL ALCOHOL METHOTREXATE vs METHYLCOBALAMIN METHOTREXATE vs METHYLDOPA

Related Pages

METHOTREXATE Full Profile All Headache Reports All Drugs Causing Headache METHOTREXATE Demographics