Does APREMILAST Cause Malaise? 4,020 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 4,020 reports of Malaise have been filed in association with APREMILAST (Otezla). This represents 2.9% of all adverse event reports for APREMILAST.
4,020
Reports of Malaise with APREMILAST
2.9%
of all APREMILAST reports
1,233
Deaths
1,467
Hospitalizations
How Dangerous Is Malaise From APREMILAST?
Of the 4,020 reports, 1,233 (30.7%) resulted in death, 1,467 (36.5%) required hospitalization, and 1,276 (31.7%) were considered life-threatening.
Is Malaise Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 4,020 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Malaise?
ADALIMUMAB (15,965)
ETANERCEPT (13,600)
METHOTREXATE (9,970)
TOFACITINIB (9,040)
SECUKINUMAB (8,570)
INFLIXIMAB (7,477)
RITUXIMAB (6,587)
PREGABALIN (6,320)
PREDNISONE (6,319)
ABATACEPT (6,251)
Which APREMILAST Alternatives Have Lower Malaise Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA