Does AFATINIB Cause Gastrointestinal toxicity? 30 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 30 reports of Gastrointestinal toxicity have been filed in association with AFATINIB (Gilotrif). This represents 0.5% of all adverse event reports for AFATINIB.
30
Reports of Gastrointestinal toxicity with AFATINIB
0.5%
of all AFATINIB reports
11
Deaths
6
Hospitalizations
How Dangerous Is Gastrointestinal toxicity From AFATINIB?
Of the 30 reports, 11 (36.7%) resulted in death, 6 (20.0%) required hospitalization.
Is Gastrointestinal toxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AFATINIB. However, 30 reports have been filed with the FAERS database.
What Other Side Effects Does AFATINIB Cause?
Diarrhoea (2,001)
Malignant neoplasm progression (1,622)
Rash (808)
Stomatitis (468)
Death (443)
Nausea (430)
Decreased appetite (412)
Vomiting (381)
Paronychia (344)
Dehydration (323)
What Other Drugs Cause Gastrointestinal toxicity?
CAPECITABINE (368)
FLUOROURACIL (358)
METHOTREXATE (345)
OXALIPLATIN (314)
CYCLOPHOSPHAMIDE (266)
RITUXIMAB (262)
CISPLATIN (251)
DOXORUBICIN (242)
IRINOTECAN (232)
CARBOPLATIN (231)
Which AFATINIB Alternatives Have Lower Gastrointestinal toxicity Risk?
AFATINIB vs AFINITOR
AFATINIB vs AFLIBERCEPT
AFATINIB vs AGALSIDASE ALFA
AFATINIB vs AGALSIDASE BETA
AFATINIB vs AGOMELATINE