Does AFATINIB Cause Metastases to bone? 82 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 82 reports of Metastases to bone have been filed in association with AFATINIB (Gilotrif). This represents 1.4% of all adverse event reports for AFATINIB.
82
Reports of Metastases to bone with AFATINIB
1.4%
of all AFATINIB reports
24
Deaths
15
Hospitalizations
How Dangerous Is Metastases to bone From AFATINIB?
Of the 82 reports, 24 (29.3%) resulted in death, 15 (18.3%) required hospitalization, and 2 (2.4%) were considered life-threatening.
Is Metastases to bone Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AFATINIB. However, 82 reports have been filed with the FAERS database.
What Other Side Effects Does AFATINIB Cause?
Diarrhoea (2,001)
Malignant neoplasm progression (1,622)
Rash (808)
Stomatitis (468)
Death (443)
Nausea (430)
Decreased appetite (412)
Vomiting (381)
Paronychia (344)
Dehydration (323)
What Other Drugs Cause Metastases to bone?
LETROZOLE (1,735)
RIBOCICLIB (1,538)
FULVESTRANT (1,525)
ZOLEDRONIC ACID (1,087)
DENOSUMAB (1,053)
TAMOXIFEN (894)
LEUPROLIDE (848)
EVEROLIMUS (845)
PACLITAXEL (820)
PALBOCICLIB (793)
Which AFATINIB Alternatives Have Lower Metastases to bone Risk?
AFATINIB vs AFINITOR
AFATINIB vs AFLIBERCEPT
AFATINIB vs AGALSIDASE ALFA
AFATINIB vs AGALSIDASE BETA
AFATINIB vs AGOMELATINE