Metastases to bone: Which Medications Cause It? (12,558 Reports Across 393 Drugs)
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Metastases to bone has been reported as an adverse event with 393 different drugs in the FDA's FAERS database, with 12,558 total reports. 2,298 of these reports resulted in death.The drugs most commonly associated with Metastases to bone are LETROZOLE, RIBOCICLIB, and FULVESTRANT.
12,558
Total Reports
393
Drugs Involved
2,298
Deaths
2,886
Hospitalizations
61.5 yrs
Average Patient Age
61.3% / 38.7%
Female / Male
Which Drugs Cause Metastases to bone Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| LETROZOLE | 1,735 | 5.6% | 130 | 294 | 72 |
| RIBOCICLIB | 1,538 | 5.5% | 148 | 321 | 75 |
| FULVESTRANT | 1,525 | 8.6% | 96 | 208 | 51 |
| ZOLEDRONIC ACID | 1,087 | 3.2% | 123 | 181 | 35 |
| DENOSUMAB | 1,053 | 0.7% | 113 | 184 | 31 |
| TAMOXIFEN | 894 | 9.8% | 46 | 53 | 18 |
| LEUPROLIDE | 848 | 1.2% | 154 | 168 | 9 |
| EVEROLIMUS | 845 | 2.1% | 140 | 173 | 21 |
| PACLITAXEL | 820 | 1.1% | 120 | 132 | 42 |
| PALBOCICLIB | 793 | 0.9% | 30 | 88 | 33 |
| CAPECITABINE | 763 | 1.2% | 110 | 100 | 38 |
| ANASTROZOLE | 758 | 6.7% | 38 | 77 | 28 |
| DOCETAXEL | 699 | 1.1% | 97 | 84 | 10 |
| TRASTUZUMAB | 531 | 1.1% | 85 | 86 | 14 |
| CYCLOPHOSPHAMIDE | 526 | 0.4% | 35 | 49 | 22 |
| EXEMESTANE | 438 | 4.2% | 25 | 35 | 14 |
| BEVACIZUMAB | 406 | 0.5% | 148 | 85 | 15 |
| GOSERELIN | 397 | 6.2% | 34 | 69 | 2 |
| CARBOPLATIN | 386 | 0.5% | 61 | 65 | 10 |
| DOXORUBICIN | 382 | 0.5% | 29 | 35 | 23 |