Does AFATINIB Cause Nephrolithiasis? 5 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5 reports of Nephrolithiasis have been filed in association with AFATINIB (Gilotrif). This represents 0.1% of all adverse event reports for AFATINIB.
5
Reports of Nephrolithiasis with AFATINIB
0.1%
of all AFATINIB reports
1
Deaths
4
Hospitalizations
How Dangerous Is Nephrolithiasis From AFATINIB?
Of the 5 reports, 1 (20.0%) resulted in death, 4 (80.0%) required hospitalization.
Is Nephrolithiasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AFATINIB. However, 5 reports have been filed with the FAERS database.
What Other Side Effects Does AFATINIB Cause?
Diarrhoea (2,001)
Malignant neoplasm progression (1,622)
Rash (808)
Stomatitis (468)
Death (443)
Nausea (430)
Decreased appetite (412)
Vomiting (381)
Paronychia (344)
Dehydration (323)
What Other Drugs Cause Nephrolithiasis?
ADALIMUMAB (2,416)
ETANERCEPT (1,292)
INFLIXIMAB (981)
METHOTREXATE (979)
ABATACEPT (788)
TOPIRAMATE (768)
CERTOLIZUMAB PEGOL (735)
RITUXIMAB (709)
TOFACITINIB (699)
SODIUM OXYBATE (698)
Which AFATINIB Alternatives Have Lower Nephrolithiasis Risk?
AFATINIB vs AFINITOR
AFATINIB vs AFLIBERCEPT
AFATINIB vs AGALSIDASE ALFA
AFATINIB vs AGALSIDASE BETA
AFATINIB vs AGOMELATINE