Does AFATINIB Cause Pancytopenia? 22 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 22 reports of Pancytopenia have been filed in association with AFATINIB (Gilotrif). This represents 0.4% of all adverse event reports for AFATINIB.
22
Reports of Pancytopenia with AFATINIB
0.4%
of all AFATINIB reports
10
Deaths
13
Hospitalizations
How Dangerous Is Pancytopenia From AFATINIB?
Of the 22 reports, 10 (45.5%) resulted in death, 13 (59.1%) required hospitalization, and 1 (4.5%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AFATINIB. However, 22 reports have been filed with the FAERS database.
What Other Side Effects Does AFATINIB Cause?
Diarrhoea (2,001)
Malignant neoplasm progression (1,622)
Rash (808)
Stomatitis (468)
Death (443)
Nausea (430)
Decreased appetite (412)
Vomiting (381)
Paronychia (344)
Dehydration (323)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which AFATINIB Alternatives Have Lower Pancytopenia Risk?
AFATINIB vs AFINITOR
AFATINIB vs AFLIBERCEPT
AFATINIB vs AGALSIDASE ALFA
AFATINIB vs AGALSIDASE BETA
AFATINIB vs AGOMELATINE