Does METHOTREXATE Cause Pancytopenia? 5,377 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5,377 reports of Pancytopenia have been filed in association with METHOTREXATE (Methotrexate). This represents 2.1% of all adverse event reports for METHOTREXATE.
5,377
Reports of Pancytopenia with METHOTREXATE
2.1%
of all METHOTREXATE reports
1,357
Deaths
3,525
Hospitalizations
How Dangerous Is Pancytopenia From METHOTREXATE?
Of the 5,377 reports, 1,357 (25.2%) resulted in death, 3,525 (65.6%) required hospitalization, and 986 (18.3%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
Yes, Pancytopenia is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Pancytopenia?
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
CYTARABINE (1,596)
Which METHOTREXATE Alternatives Have Lower Pancytopenia Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA