Does AFATINIB Cause Skin toxicity? 79 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 79 reports of Skin toxicity have been filed in association with AFATINIB (Gilotrif). This represents 1.3% of all adverse event reports for AFATINIB.
79
Reports of Skin toxicity with AFATINIB
1.3%
of all AFATINIB reports
21
Deaths
18
Hospitalizations
How Dangerous Is Skin toxicity From AFATINIB?
Of the 79 reports, 21 (26.6%) resulted in death, 18 (22.8%) required hospitalization, and 1 (1.3%) were considered life-threatening.
Is Skin toxicity Listed in the Official Label?
Yes, Skin toxicity is listed as a known adverse reaction in the official FDA drug label for AFATINIB.
What Other Side Effects Does AFATINIB Cause?
Diarrhoea (2,001)
Malignant neoplasm progression (1,622)
Rash (808)
Stomatitis (468)
Death (443)
Nausea (430)
Decreased appetite (412)
Vomiting (381)
Paronychia (344)
Dehydration (323)
What Other Drugs Cause Skin toxicity?
PANITUMUMAB (728)
FLUOROURACIL (597)
OXALIPLATIN (469)
LEUCOVORIN (366)
CARBOPLATIN (322)
IRINOTECAN (308)
PACLITAXEL (305)
PEMBROLIZUMAB (299)
CAPECITABINE (269)
CETUXIMAB (254)
Which AFATINIB Alternatives Have Lower Skin toxicity Risk?
AFATINIB vs AFINITOR
AFATINIB vs AFLIBERCEPT
AFATINIB vs AGALSIDASE ALFA
AFATINIB vs AGALSIDASE BETA
AFATINIB vs AGOMELATINE