Skin toxicity: Which Medications Cause It? (4,235 Reports Across 211 Drugs)
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Skin toxicity has been reported as an adverse event with 211 different drugs in the FDA's FAERS database, with 4,235 total reports. 374 of these reports resulted in death.The drugs most commonly associated with Skin toxicity are PANITUMUMAB, FLUOROURACIL, and OXALIPLATIN.
4,235
Total Reports
211
Drugs Involved
374
Deaths
843
Hospitalizations
57.4 yrs
Average Patient Age
50.8% / 49.2%
Female / Male
Which Drugs Cause Skin toxicity Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| PANITUMUMAB | 728 | 6.7% | 38 | 59 | 35 |
| FLUOROURACIL | 597 | 1.1% | 27 | 84 | 30 |
| OXALIPLATIN | 469 | 0.8% | 20 | 61 | 17 |
| LEUCOVORIN | 366 | 1.5% | 11 | 52 | 19 |
| CARBOPLATIN | 322 | 0.4% | 44 | 76 | 4 |
| IRINOTECAN | 308 | 1.1% | 14 | 53 | 17 |
| PACLITAXEL | 305 | 0.4% | 33 | 97 | 8 |
| PEMBROLIZUMAB | 299 | 0.4% | 29 | 102 | 10 |
| CAPECITABINE | 269 | 0.4% | 23 | 48 | 1 |
| CETUXIMAB | 254 | 1.8% | 15 | 33 | 6 |
| CYCLOPHOSPHAMIDE | 240 | 0.2% | 35 | 43 | 20 |
| BEVACIZUMAB | 224 | 0.3% | 29 | 28 | 7 |
| DOCETAXEL | 212 | 0.3% | 17 | 48 | 19 |
| NIVOLUMAB | 177 | 0.2% | 12 | 46 | 10 |
| METHOTREXATE | 172 | 0.1% | 19 | 56 | 35 |
| DOXORUBICIN | 167 | 0.2% | 23 | 49 | 19 |
| CYTARABINE | 157 | 0.4% | 22 | 21 | 17 |
| VEMURAFENIB | 147 | 1.7% | 6 | 21 | 4 |
| ETOPOSIDE | 138 | 0.3% | 20 | 27 | 7 |
| TRASTUZUMAB | 138 | 0.3% | 11 | 42 | 1 |