Does METHOTREXATE Cause Skin toxicity? 172 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 172 reports of Skin toxicity have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
172
Reports of Skin toxicity with METHOTREXATE
0.1%
of all METHOTREXATE reports
19
Deaths
56
Hospitalizations
How Dangerous Is Skin toxicity From METHOTREXATE?
Of the 172 reports, 19 (11.0%) resulted in death, 56 (32.6%) required hospitalization, and 35 (20.3%) were considered life-threatening.
Is Skin toxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 172 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Skin toxicity?
PANITUMUMAB (728)
FLUOROURACIL (597)
OXALIPLATIN (469)
LEUCOVORIN (366)
CARBOPLATIN (322)
IRINOTECAN (308)
PACLITAXEL (305)
PEMBROLIZUMAB (299)
CAPECITABINE (269)
CETUXIMAB (254)
Which METHOTREXATE Alternatives Have Lower Skin toxicity Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA