AFINITOR for Off label use: Side Effects & Safety Data
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There are 26 adverse event reports in the FDA FAERS database where AFINITOR was used for Off label use.
Most Reported Side Effects for AFINITOR
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 192 | 27.1% | 192 | 22 |
| Malignant neoplasm progression | 70 | 9.9% | 47 | 25 |
| Dyspnoea | 58 | 8.2% | 19 | 28 |
| Stomatitis | 57 | 8.1% | 17 | 17 |
| Diarrhoea | 47 | 6.6% | 11 | 27 |
| Fatigue | 44 | 6.2% | 9 | 16 |
| Cough | 34 | 4.8% | 8 | 16 |
| Pyrexia | 34 | 4.8% | 10 | 29 |
| Rash | 29 | 4.1% | 7 | 10 |
| Nausea | 28 | 4.0% | 7 | 15 |
| Drug ineffective | 27 | 3.8% | 5 | 5 |
| Anaemia | 26 | 3.7% | 11 | 14 |
| General physical health deterioration | 26 | 3.7% | 17 | 14 |
| Pneumonitis | 26 | 3.7% | 9 | 10 |
| Asthenia | 25 | 3.5% | 13 | 19 |
Other Indications for AFINITOR
Breast cancer (153)
Breast cancer metastatic (85)
Pancreatic neuroendocrine tumour (41)
Renal cancer (35)
Metastatic renal cell carcinoma (27)
Renal cell carcinoma (27)
Neuroendocrine tumour (24)
Angiomyolipoma (17)
Neoplasm malignant (13)
Breast cancer female (11)
Other Drugs Used for Off label use
LENALIDOMIDE (5,767)
ECULIZUMAB (3,550)
CERTOLIZUMAB PEGOL (2,256)
ABOBOTULINUMTOXINA (2,170)
LEVETIRACETAM (2,161)
APREMILAST (1,995)
PROPRANOLOL (1,576)
CETIRIZINE (1,416)
HUMAN IMMUNOGLOBULIN G (1,129)
THALIDOMIDE (1,033)