AFLIBERCEPT for Choroidal neovascularisation: Side Effects & Safety Data
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There are 2,953 adverse event reports in the FDA FAERS database where AFLIBERCEPT was used for Choroidal neovascularisation.
Most Reported Side Effects for AFLIBERCEPT
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 7,669 | 28.5% | 7,666 | 73 |
| Visual impairment | 1,836 | 6.8% | 14 | 167 |
| Blindness | 1,337 | 5.0% | 7 | 134 |
| Endophthalmitis | 1,289 | 4.8% | 5 | 203 |
| Off label use | 1,156 | 4.3% | 115 | 140 |
| Eye pain | 1,057 | 3.9% | 5 | 120 |
| Product dose omission issue | 1,051 | 3.9% | 4 | 40 |
| Blindness unilateral | 1,012 | 3.8% | 11 | 88 |
| Vision blurred | 1,012 | 3.8% | 10 | 97 |
| Visual acuity reduced | 993 | 3.7% | 8 | 89 |
| Blindness transient | 987 | 3.7% | 3 | 30 |
| Drug ineffective | 961 | 3.6% | 18 | 56 |
| Eye inflammation | 875 | 3.3% | 4 | 44 |
| Eye haemorrhage | 739 | 2.8% | 2 | 50 |
| Intraocular pressure increased | 690 | 2.6% | 2 | 33 |
Other Indications for AFLIBERCEPT
Neovascular age-related macular degeneration (8,685)
Product used for unknown indication (6,271)
Diabetic retinal oedema (3,407)
Age-related macular degeneration (2,220)
Retinal vein occlusion (1,928)
Diabetic retinopathy (1,720)
Macular oedema (1,362)
Macular degeneration (945)
Colorectal cancer metastatic (915)
Polypoidal choroidal vasculopathy (193)
Other Drugs Used for Choroidal neovascularisation
RANIBIZUMAB (1,364)
FARICIMAB\FARICIMAB-SVOA (306)
BEVACIZUMAB (302)
BROLUCIZUMAB-DBLL (104)
BROLUCIZUMAB (102)
FARICIMAB-SVOA (65)
VERTEPORFIN (42)
AVASTIN (12)
LUCENTIS (11)
TRIAMCINOLONE ACETONIDE (10)