Does AFLIBERCEPT Cause Off label use? 1,156 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,156 reports of Off label use have been filed in association with AFLIBERCEPT (EYLEA). This represents 4.3% of all adverse event reports for AFLIBERCEPT.
1,156
Reports of Off label use with AFLIBERCEPT
4.3%
of all AFLIBERCEPT reports
115
Deaths
140
Hospitalizations
How Dangerous Is Off label use From AFLIBERCEPT?
Of the 1,156 reports, 115 (9.9%) resulted in death, 140 (12.1%) required hospitalization, and 8 (0.7%) were considered life-threatening.
Is Off label use Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AFLIBERCEPT. However, 1,156 reports have been filed with the FAERS database.
What Other Side Effects Does AFLIBERCEPT Cause?
Death (7,669)
Visual impairment (1,836)
Blindness (1,337)
Endophthalmitis (1,289)
Eye pain (1,057)
Product dose omission issue (1,051)
Blindness unilateral (1,012)
Vision blurred (1,012)
Visual acuity reduced (993)
Blindness transient (987)
What Other Drugs Cause Off label use?
RITUXIMAB (39,751)
INFLIXIMAB (34,801)
DENOSUMAB (34,612)
METHOTREXATE (24,020)
VEDOLIZUMAB (21,017)
ETANERCEPT (20,178)
TOCILIZUMAB (18,256)
PREDNISONE (17,867)
LENALIDOMIDE (17,017)
ADALIMUMAB (16,417)
Which AFLIBERCEPT Alternatives Have Lower Off label use Risk?
AFLIBERCEPT vs AGALSIDASE ALFA
AFLIBERCEPT vs AGALSIDASE BETA
AFLIBERCEPT vs AGOMELATINE
AFLIBERCEPT vs ALAWAY
AFLIBERCEPT vs ALBENDAZOLE