Does ALLOPURINOL Cause Diastolic dysfunction? 105 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 105 reports of Diastolic dysfunction have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.6% of all adverse event reports for ALLOPURINOL.
105
Reports of Diastolic dysfunction with ALLOPURINOL
0.6%
of all ALLOPURINOL reports
2
Deaths
99
Hospitalizations
How Dangerous Is Diastolic dysfunction From ALLOPURINOL?
Of the 105 reports, 2 (1.9%) resulted in death, 99 (94.3%) required hospitalization, and 58 (55.2%) were considered life-threatening.
Is Diastolic dysfunction Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 105 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Diastolic dysfunction?
BISOPROLOL (198)
PREDNISONE (187)
PANTOPRAZOLE (186)
ALBUTEROL (173)
ASPIRIN (167)
FUROSEMIDE (152)
AMLODIPINE (143)
MONTELUKAST (137)
UMECLIDINIUM (129)
APIXABAN (120)
Which ALLOPURINOL Alternatives Have Lower Diastolic dysfunction Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN