Does ALLOPURINOL Cause Pruritus? 836 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 836 reports of Pruritus have been filed in association with ALLOPURINOL (Allopurinol). This represents 4.4% of all adverse event reports for ALLOPURINOL.
836
Reports of Pruritus with ALLOPURINOL
4.4%
of all ALLOPURINOL reports
70
Deaths
474
Hospitalizations
How Dangerous Is Pruritus From ALLOPURINOL?
Of the 836 reports, 70 (8.4%) resulted in death, 474 (56.7%) required hospitalization, and 78 (9.3%) were considered life-threatening.
Is Pruritus Listed in the Official Label?
Yes, Pruritus is listed as a known adverse reaction in the official FDA drug label for ALLOPURINOL.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Diarrhoea (819)
Drug ineffective (780)
Stevens-johnson syndrome (715)
What Other Drugs Cause Pruritus?
DUPILUMAB (44,279)
ADAPALENE (12,072)
ADALIMUMAB (9,644)
AVOBENZONE\OCTISALATE\OCTOCRYLENE (9,439)
SECUKINUMAB (8,755)
ETANERCEPT (8,047)
METHOTREXATE (7,526)
LENALIDOMIDE (6,304)
TOCILIZUMAB (5,973)
RITUXIMAB (5,548)
Which ALLOPURINOL Alternatives Have Lower Pruritus Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN