Does METHOTREXATE Cause Pruritus? 7,526 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 7,526 reports of Pruritus have been filed in association with METHOTREXATE (Methotrexate). This represents 3.0% of all adverse event reports for METHOTREXATE.
7,526
Reports of Pruritus with METHOTREXATE
3.0%
of all METHOTREXATE reports
1,185
Deaths
2,472
Hospitalizations
How Dangerous Is Pruritus From METHOTREXATE?
Of the 7,526 reports, 1,185 (15.7%) resulted in death, 2,472 (32.8%) required hospitalization, and 1,466 (19.5%) were considered life-threatening.
Is Pruritus Listed in the Official Label?
Yes, Pruritus is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Pruritus?
DUPILUMAB (44,279)
ADAPALENE (12,072)
ADALIMUMAB (9,644)
AVOBENZONE\OCTISALATE\OCTOCRYLENE (9,439)
SECUKINUMAB (8,755)
ETANERCEPT (8,047)
LENALIDOMIDE (6,304)
TOCILIZUMAB (5,973)
RITUXIMAB (5,548)
CETIRIZINE (5,482)
Which METHOTREXATE Alternatives Have Lower Pruritus Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA