Pruritus: Which Medications Cause It? (278,736 Reports Across 2,501 Drugs)
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Pruritus has been reported as an adverse event with 2,501 different drugs in the FDA's FAERS database, with 278,736 total reports. 4,779 of these reports resulted in death.The drugs most commonly associated with Pruritus are DUPILUMAB, ADAPALENE, and ADALIMUMAB.
278,736
Total Reports
2,501
Drugs Involved
4,779
Deaths
37,068
Hospitalizations
52.8 yrs
Average Patient Age
68.0% / 32.0%
Female / Male
Which Drugs Cause Pruritus Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| DUPILUMAB | 44,279 | 11.7% | 53 | 1,105 | 32 |
| ADAPALENE | 12,072 | 6.7% | 0 | 9 | 0 |
| ADALIMUMAB | 9,644 | 1.9% | 1,287 | 2,668 | 1,300 |
| AVOBENZONE\OCTISALATE\OCTOCRYLENE | 9,439 | 7.2% | 0 | 3 | 0 |
| SECUKINUMAB | 8,755 | 5.8% | 1,088 | 1,921 | 1,289 |
| ETANERCEPT | 8,047 | 2.3% | 1,062 | 1,681 | 1,010 |
| METHOTREXATE | 7,526 | 3.0% | 1,185 | 2,472 | 1,466 |
| LENALIDOMIDE | 6,304 | 1.8% | 64 | 622 | 44 |
| TOCILIZUMAB | 5,973 | 6.1% | 1,363 | 2,048 | 1,283 |
| RITUXIMAB | 5,548 | 3.1% | 1,219 | 2,398 | 1,364 |
| CETIRIZINE | 5,482 | 11.5% | 1,045 | 1,773 | 1,308 |
| CERTOLIZUMAB PEGOL | 5,370 | 5.4% | 1,021 | 1,635 | 1,212 |
| INFLIXIMAB | 5,370 | 3.8% | 1,044 | 2,165 | 1,257 |
| ABATACEPT | 5,339 | 4.6% | 1,022 | 1,807 | 1,292 |
| OMALIZUMAB | 5,224 | 8.2% | 32 | 1,202 | 254 |
| ACETAMINOPHEN | 5,037 | 3.7% | 1,218 | 1,840 | 1,165 |
| LEFLUNOMIDE | 4,515 | 8.0% | 1,043 | 1,816 | 1,328 |
| PREDNISONE | 4,341 | 2.7% | 1,127 | 1,980 | 1,303 |
| DICLOFENAC | 4,261 | 4.9% | 1,192 | 1,921 | 1,336 |
| GOLIMUMAB | 4,134 | 6.0% | 1,046 | 1,572 | 1,174 |