Does ALLOPURINOL Cause Stevens-johnson syndrome? 715 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 715 reports of Stevens-johnson syndrome have been filed in association with ALLOPURINOL (Allopurinol). This represents 3.8% of all adverse event reports for ALLOPURINOL.
715
Reports of Stevens-johnson syndrome with ALLOPURINOL
3.8%
of all ALLOPURINOL reports
178
Deaths
479
Hospitalizations
How Dangerous Is Stevens-johnson syndrome From ALLOPURINOL?
Of the 715 reports, 178 (24.9%) resulted in death, 479 (67.0%) required hospitalization, and 175 (24.5%) were considered life-threatening.
Is Stevens-johnson syndrome Listed in the Official Label?
Yes, Stevens-johnson syndrome is listed as a known adverse reaction in the official FDA drug label for ALLOPURINOL.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Stevens-johnson syndrome?
LAMOTRIGINE (1,384)
IBUPROFEN (711)
SULFAMETHOXAZOLE\TRIMETHOPRIM (665)
ACETAMINOPHEN (649)
CARBAMAZEPINE (440)
PEMBROLIZUMAB (395)
LEVETIRACETAM (374)
CIPROFLOXACIN (349)
VANCOMYCIN (313)
PHENYTOIN (306)
Which ALLOPURINOL Alternatives Have Lower Stevens-johnson syndrome Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN