Does PHENYTOIN Cause Stevens-johnson syndrome? 306 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 306 reports of Stevens-johnson syndrome have been filed in association with PHENYTOIN (PHENYTOIN SODIUM). This represents 2.1% of all adverse event reports for PHENYTOIN.
306
Reports of Stevens-johnson syndrome with PHENYTOIN
2.1%
of all PHENYTOIN reports
40
Deaths
203
Hospitalizations
How Dangerous Is Stevens-johnson syndrome From PHENYTOIN?
Of the 306 reports, 40 (13.1%) resulted in death, 203 (66.3%) required hospitalization, and 72 (23.5%) were considered life-threatening.
Is Stevens-johnson syndrome Listed in the Official Label?
Yes, Stevens-johnson syndrome is listed as a known adverse reaction in the official FDA drug label for PHENYTOIN.
What Other Side Effects Does PHENYTOIN Cause?
Drug ineffective (2,753)
Seizure (1,907)
Toxicity to various agents (1,248)
Drug hypersensitivity (898)
Off label use (852)
Drug interaction (772)
Drug reaction with eosinophilia and systemic symptoms (673)
Status epilepticus (544)
Fall (436)
Rash (414)
What Other Drugs Cause Stevens-johnson syndrome?
LAMOTRIGINE (1,384)
ALLOPURINOL (715)
IBUPROFEN (711)
SULFAMETHOXAZOLE\TRIMETHOPRIM (665)
ACETAMINOPHEN (649)
CARBAMAZEPINE (440)
PEMBROLIZUMAB (395)
LEVETIRACETAM (374)
CIPROFLOXACIN (349)
VANCOMYCIN (313)
Which PHENYTOIN Alternatives Have Lower Stevens-johnson syndrome Risk?
PHENYTOIN vs PHLEUM PRATENSE POLLEN
PHENYTOIN vs PHLOROGLUCINOL
PHENYTOIN vs PHLOROGLUCINOL\1,3,5-TRIMETHOXYBENZENE
PHENYTOIN vs PHOLCODINE
PHENYTOIN vs PHOSPHORUS