Does PEMBROLIZUMAB Cause Stevens-johnson syndrome? 395 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 395 reports of Stevens-johnson syndrome have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.5% of all adverse event reports for PEMBROLIZUMAB.
395
Reports of Stevens-johnson syndrome with PEMBROLIZUMAB
0.5%
of all PEMBROLIZUMAB reports
118
Deaths
288
Hospitalizations
How Dangerous Is Stevens-johnson syndrome From PEMBROLIZUMAB?
Of the 395 reports, 118 (29.9%) resulted in death, 288 (72.9%) required hospitalization, and 89 (22.5%) were considered life-threatening.
Is Stevens-johnson syndrome Listed in the Official Label?
Yes, Stevens-johnson syndrome is listed as a known adverse reaction in the official FDA drug label for PEMBROLIZUMAB.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Stevens-johnson syndrome?
LAMOTRIGINE (1,384)
ALLOPURINOL (715)
IBUPROFEN (711)
SULFAMETHOXAZOLE\TRIMETHOPRIM (665)
ACETAMINOPHEN (649)
CARBAMAZEPINE (440)
LEVETIRACETAM (374)
CIPROFLOXACIN (349)
VANCOMYCIN (313)
PHENYTOIN (306)
Which PEMBROLIZUMAB Alternatives Have Lower Stevens-johnson syndrome Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G