Does ALLOPURINOL Cause Hyperkalaemia? 356 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 356 reports of Hyperkalaemia have been filed in association with ALLOPURINOL (Allopurinol). This represents 1.9% of all adverse event reports for ALLOPURINOL.
356
Reports of Hyperkalaemia with ALLOPURINOL
1.9%
of all ALLOPURINOL reports
47
Deaths
220
Hospitalizations
How Dangerous Is Hyperkalaemia From ALLOPURINOL?
Of the 356 reports, 47 (13.2%) resulted in death, 220 (61.8%) required hospitalization, and 69 (19.4%) were considered life-threatening.
Is Hyperkalaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 356 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Hyperkalaemia?
METFORMIN (2,565)
SPIRONOLACTONE (2,518)
FUROSEMIDE (2,035)
RAMIPRIL (1,383)
SACUBITRIL\VALSARTAN (1,192)
SULFAMETHOXAZOLE\TRIMETHOPRIM (1,036)
LISINOPRIL (948)
POTASSIUM (944)
BISOPROLOL (850)
TACROLIMUS (713)
Which ALLOPURINOL Alternatives Have Lower Hyperkalaemia Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN