Does ALLOPURINOL Cause Hyperphosphataemia? 139 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 139 reports of Hyperphosphataemia have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.7% of all adverse event reports for ALLOPURINOL.
139
Reports of Hyperphosphataemia with ALLOPURINOL
0.7%
of all ALLOPURINOL reports
121
Deaths
129
Hospitalizations
How Dangerous Is Hyperphosphataemia From ALLOPURINOL?
Of the 139 reports, 121 (87.1%) resulted in death, 129 (92.8%) required hospitalization, and 102 (73.4%) were considered life-threatening.
Is Hyperphosphataemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 139 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Hyperphosphataemia?
LANSOPRAZOLE (138)
ACETAMINOPHEN (132)
SEVELAMER (129)
ONDANSETRON (127)
CALCITRIOL (125)
IPRATROPIUM (123)
ALBUTEROL (122)
METRONIDAZOLE (120)
HYDROMORPHONE (118)
PHYTONADIONE (118)
Which ALLOPURINOL Alternatives Have Lower Hyperphosphataemia Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN