Does ALLOPURINOL Cause Hypophosphataemia? 149 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 149 reports of Hypophosphataemia have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.8% of all adverse event reports for ALLOPURINOL.
149
Reports of Hypophosphataemia with ALLOPURINOL
0.8%
of all ALLOPURINOL reports
122
Deaths
138
Hospitalizations
How Dangerous Is Hypophosphataemia From ALLOPURINOL?
Of the 149 reports, 122 (81.9%) resulted in death, 138 (92.6%) required hospitalization, and 110 (73.8%) were considered life-threatening.
Is Hypophosphataemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 149 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Hypophosphataemia?
FERRIC CARBOXYMALTOSE (1,046)
ADEFOVIR DIPIVOXIL (368)
DENOSUMAB (322)
ZOLEDRONIC ACID (235)
LAMIVUDINE (205)
CYCLOPHOSPHAMIDE (196)
TENOFOVIR DISOPROXIL (192)
DEXAMETHASONE (186)
ACETAMINOPHEN (169)
LANSOPRAZOLE (159)
Which ALLOPURINOL Alternatives Have Lower Hypophosphataemia Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN