Does ALLOPURINOL Cause Melaena? 122 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 122 reports of Melaena have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.6% of all adverse event reports for ALLOPURINOL.
122
Reports of Melaena with ALLOPURINOL
0.6%
of all ALLOPURINOL reports
58
Deaths
100
Hospitalizations
How Dangerous Is Melaena From ALLOPURINOL?
Of the 122 reports, 58 (47.5%) resulted in death, 100 (82.0%) required hospitalization, and 6 (4.9%) were considered life-threatening.
Is Melaena Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 122 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Melaena?
ASPIRIN (2,001)
CLOPIDOGREL BISULFATE (1,547)
RIVAROXABAN (1,405)
APIXABAN (1,156)
WARFARIN (930)
IBUPROFEN (810)
DABIGATRAN ETEXILATE (700)
DICLOFENAC (576)
NAPROXEN (291)
FUROSEMIDE (272)
Which ALLOPURINOL Alternatives Have Lower Melaena Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN