Does ALTEPLASE Cause Hypotension? 242 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 242 reports of Hypotension have been filed in association with ALTEPLASE (Activase). This represents 1.9% of all adverse event reports for ALTEPLASE.
242
Reports of Hypotension with ALTEPLASE
1.9%
of all ALTEPLASE reports
48
Deaths
80
Hospitalizations
How Dangerous Is Hypotension From ALTEPLASE?
Of the 242 reports, 48 (19.8%) resulted in death, 80 (33.1%) required hospitalization, and 42 (17.4%) were considered life-threatening.
Is Hypotension Listed in the Official Label?
Yes, Hypotension is listed as a known adverse reaction in the official FDA drug label for ALTEPLASE.
What Other Side Effects Does ALTEPLASE Cause?
No adverse event (2,456)
Off label use (1,752)
Gingival bleeding (1,018)
Cerebral haemorrhage (819)
Death (818)
Haemorrhage intracranial (615)
Angioedema (603)
Haemorrhage (536)
Drug ineffective (524)
Haemorrhagic transformation stroke (496)
What Other Drugs Cause Hypotension?
SACUBITRIL\VALSARTAN (11,718)
AMLODIPINE (6,504)
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (4,694)
FUROSEMIDE (4,468)
TREPROSTINIL (4,412)
METOPROLOL (3,213)
RITUXIMAB (3,208)
METFORMIN (3,116)
LENALIDOMIDE (2,920)
ACETAMINOPHEN (2,817)
Which ALTEPLASE Alternatives Have Lower Hypotension Risk?
ALTEPLASE vs ALTERNARIA ALTERNATA
ALTEPLASE vs ALTHIAZIDE
ALTEPLASE vs ALTHIAZIDE\SPIRONOLACTONE
ALTEPLASE vs ALUMINUM
ALTEPLASE vs ALUMINUM HYDROXIDE