Does ALTEPLASE Cause Neurological decompensation? 168 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 168 reports of Neurological decompensation have been filed in association with ALTEPLASE (Activase). This represents 1.3% of all adverse event reports for ALTEPLASE.
168
Reports of Neurological decompensation with ALTEPLASE
1.3%
of all ALTEPLASE reports
26
Deaths
23
Hospitalizations
How Dangerous Is Neurological decompensation From ALTEPLASE?
Of the 168 reports, 26 (15.5%) resulted in death, 23 (13.7%) required hospitalization, and 12 (7.1%) were considered life-threatening.
Is Neurological decompensation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALTEPLASE. However, 168 reports have been filed with the FAERS database.
What Other Side Effects Does ALTEPLASE Cause?
No adverse event (2,456)
Off label use (1,752)
Gingival bleeding (1,018)
Cerebral haemorrhage (819)
Death (818)
Haemorrhage intracranial (615)
Angioedema (603)
Haemorrhage (536)
Drug ineffective (524)
Haemorrhagic transformation stroke (496)
What Other Drugs Cause Neurological decompensation?
RITUXIMAB (115)
METHOTREXATE (93)
CYCLOPHOSPHAMIDE (91)
VINCRISTINE (76)
ETOPOSIDE (74)
METHYLPREDNISOLONE (70)
PREDNISONE (70)
DOXORUBICIN (68)
ACETAMINOPHEN (65)
DEXAMETHASONE (65)
Which ALTEPLASE Alternatives Have Lower Neurological decompensation Risk?
ALTEPLASE vs ALTERNARIA ALTERNATA
ALTEPLASE vs ALTHIAZIDE
ALTEPLASE vs ALTHIAZIDE\SPIRONOLACTONE
ALTEPLASE vs ALUMINUM
ALTEPLASE vs ALUMINUM HYDROXIDE