Neurological decompensation: Which Medications Cause It? (1,670 Reports Across 218 Drugs)
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Neurological decompensation has been reported as an adverse event with 218 different drugs in the FDA's FAERS database, with 1,670 total reports. 615 of these reports resulted in death.The drugs most commonly associated with Neurological decompensation are ALTEPLASE, RITUXIMAB, and METHOTREXATE.
1,670
Total Reports
218
Drugs Involved
615
Deaths
967
Hospitalizations
51.8 yrs
Average Patient Age
48.0% / 52.0%
Female / Male
Which Drugs Cause Neurological decompensation Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ALTEPLASE | 168 | 1.3% | 26 | 23 | 12 |
| RITUXIMAB | 115 | 0.1% | 58 | 72 | 31 |
| METHOTREXATE | 93 | 0.0% | 40 | 69 | 20 |
| CYCLOPHOSPHAMIDE | 91 | 0.1% | 29 | 68 | 48 |
| VINCRISTINE | 76 | 0.1% | 33 | 54 | 44 |
| ETOPOSIDE | 74 | 0.1% | 33 | 46 | 45 |
| METHYLPREDNISOLONE | 70 | 0.1% | 41 | 60 | 24 |
| PREDNISONE | 70 | 0.0% | 51 | 46 | 30 |
| DOXORUBICIN | 68 | 0.1% | 27 | 50 | 44 |
| ACETAMINOPHEN | 65 | 0.1% | 5 | 57 | 41 |
| DEXAMETHASONE | 65 | 0.1% | 43 | 25 | 24 |
| PREDNISOLONE | 54 | 0.1% | 11 | 47 | 35 |
| ASPIRIN | 52 | 0.1% | 10 | 48 | 30 |
| CYTARABINE | 51 | 0.1% | 36 | 31 | 13 |
| QUETIAPINE | 51 | 0.1% | 12 | 39 | 25 |
| BACLOFEN | 45 | 0.2% | 2 | 42 | 32 |
| TRASTUZUMAB | 45 | 0.1% | 30 | 28 | 0 |
| IBUPROFEN | 44 | 0.1% | 0 | 41 | 36 |
| LEVETIRACETAM | 40 | 0.1% | 13 | 19 | 14 |
| OLANZAPINE | 40 | 0.1% | 2 | 36 | 2 |