Does AMOXICILLIN\CLAVULANATE Cause Cholestasis? 480 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 480 reports of Cholestasis have been filed in association with AMOXICILLIN\CLAVULANATE. This represents 3.1% of all adverse event reports for AMOXICILLIN\CLAVULANATE.
480
Reports of Cholestasis with AMOXICILLIN\CLAVULANATE
3.1%
of all AMOXICILLIN\CLAVULANATE reports
21
Deaths
341
Hospitalizations
How Dangerous Is Cholestasis From AMOXICILLIN\CLAVULANATE?
Of the 480 reports, 21 (4.4%) resulted in death, 341 (71.0%) required hospitalization, and 18 (3.8%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMOXICILLIN\CLAVULANATE. However, 480 reports have been filed with the FAERS database.
What Other Side Effects Does AMOXICILLIN\CLAVULANATE Cause?
Drug hypersensitivity (1,746)
Diarrhoea (1,301)
Vomiting (812)
Nausea (766)
Rash (760)
Drug-induced liver injury (751)
Dyspnoea (750)
Drug ineffective (712)
Pruritus (645)
Pyrexia (597)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
AMOXICILLIN (326)
Which AMOXICILLIN\CLAVULANATE Alternatives Have Lower Cholestasis Risk?
AMOXICILLIN\CLAVULANATE vs AMOXICILLIN\CLAVULANIC ACID
AMOXICILLIN\CLAVULANATE vs AMOXICILLIN\OMEPRAZOLE\RIFABUTIN
AMOXICILLIN\CLAVULANATE vs AMPHETAMINE
AMOXICILLIN\CLAVULANATE vs AMPHETAMINE ASPARTATE\AMPHETAMINE ASPARTATE\AMPHETAMINE\DEXTROAMPHETAMINE SACCHARATE\DEXTROAMPHETAMINE
AMOXICILLIN\CLAVULANATE vs AMPHETAMINE ASPARTATE\AMPHETAMINE\DEXTROAMPHETAMINE SACCHARATE\DEXTROAMPHETAMINE