Does AMPHOTERICIN B Cause Pancytopenia? 247 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 247 reports of Pancytopenia have been filed in association with AMPHOTERICIN B (Amphotericin B). This represents 2.3% of all adverse event reports for AMPHOTERICIN B.
247
Reports of Pancytopenia with AMPHOTERICIN B
2.3%
of all AMPHOTERICIN B reports
68
Deaths
125
Hospitalizations
How Dangerous Is Pancytopenia From AMPHOTERICIN B?
Of the 247 reports, 68 (27.5%) resulted in death, 125 (50.6%) required hospitalization, and 39 (15.8%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMPHOTERICIN B. However, 247 reports have been filed with the FAERS database.
What Other Side Effects Does AMPHOTERICIN B Cause?
Drug ineffective (4,151)
Off label use (1,529)
Condition aggravated (603)
Acute kidney injury (596)
Multiple organ dysfunction syndrome (465)
Pyrexia (388)
Death (379)
Hypokalaemia (353)
Renal impairment (328)
Septic shock (308)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which AMPHOTERICIN B Alternatives Have Lower Pancytopenia Risk?
AMPHOTERICIN B vs AMPHOTERICIN B\DIMYRISTOYLPHOSPHATIDYLCHOLINE, DL-\DIMYRISTOYLPHOSPHATIDYLGLYCEROL, DL-
AMPHOTERICIN B vs AMPICILLIN
AMPHOTERICIN B vs AMPICILLIN\SULBACTAM
AMPHOTERICIN B vs AMPRENAVIR
AMPHOTERICIN B vs AMPYRA