Does APREMILAST Cause Aspartate aminotransferase increased? 260 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 260 reports of Aspartate aminotransferase increased have been filed in association with APREMILAST (Otezla). This represents 0.2% of all adverse event reports for APREMILAST.
260
Reports of Aspartate aminotransferase increased with APREMILAST
0.2%
of all APREMILAST reports
4
Deaths
171
Hospitalizations
How Dangerous Is Aspartate aminotransferase increased From APREMILAST?
Of the 260 reports, 4 (1.5%) resulted in death, 171 (65.8%) required hospitalization, and 2 (0.8%) were considered life-threatening.
Is Aspartate aminotransferase increased Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 260 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Aspartate aminotransferase increased?
METHOTREXATE (1,600)
RITUXIMAB (1,351)
ADALIMUMAB (1,166)
TOCILIZUMAB (975)
ETANERCEPT (939)
ACETAMINOPHEN (865)
LEFLUNOMIDE (863)
INFLIXIMAB (823)
ABATACEPT (778)
NIVOLUMAB (758)
Which APREMILAST Alternatives Have Lower Aspartate aminotransferase increased Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA